Modafinil Alternatives: 9 Natural Options for Boosting Focus

If you want to boost your productivity and focus, you’ve likely heard of Modafinil, a popular prescription medication for narcolepsy and other sleep disorders. Modafinil has become a prevalent off-label study drug sold under Provigil in recent years.

Selling Modafinil in the UK is illegal and can cause nasty side effects. Luckily, various Modafinil alternatives can provide similar benefits without worrying about potential side effects or legality.

In this blog post, we’ll introduce you to 9 natural Modafinil alternatives that are safe and effective for boosting productivity and focus. We will cover various options for your needs, from caffeine to ginkgo biloba.

We’ll also tell you about our choice for the best natural Modafinil alternative that costs less and made right here in the UK.

So, if you’re ready to take your productivity and focus to the next level, keep reading!

Spoiler Alert: You don’t want to read the following 2,500 words? Check out Brainzyme® FOCUS PRO™ as the best natural alternative to Modafinil.

This website contains affiliate links. We may earn a commission as an affiliate when you click these links and purchase or take a specific action.


  • Why Choose Natural Modafinil Alternatives?
  • Adrafinil
  • Caffeine
  • L-Theanine
  • Ginkgo Biloba
  • Brainzyme® FOCUS PRO™
  • Panax Ginseng
  • Acetyl-L-Carnitine
  • Choline
  • Bacopa Monnieri
  • What is the Best Modafinil Alternative?
  • Conclusion

Why Choose Natural Modafinil Alternatives?

There are several reasons why you might want to consider natural alternatives to Modafinil, a popular smart drug used to improve cognitive function and productivity. One reason is that Modafinil is a prescription medication that may not suit everyone. It can have adverse side effects, including anxiety, insomnia, and gastrointestinal problems, and it may not be safe for people with certain health conditions.

Additionally, long-term use of Modafinil and other smart drugs may have unknown risks and may not be the most sustainable solution for improving cognitive function. On the other hand, natural alternatives may offer similar benefits without potential adverse side effects and long-term risks.

Another reason to consider natural alternatives to Modafinil is that they may be more effective in addressing the root cause of cognitive impairment rather than just treating the symptoms. For example, if stress or anxiety is causing cognitive problems, natural remedies like L-theanine or Bacopa monnieri may be more effective in improving mental health and cognitive function.

If you want more information on using Modafinil as a smart drug, please check out our blog postModafinil UK.”


Adrafinil is the most similar nootropic to Modafinil on this list. It’s also the only synthetic nootropic.

We decided to include Adrafinil in this list because it is similar to Modafinil in the way it works but is legal to possess in the UK without a prescription.

Like Modafinil, Adrafinil was developed to treat narcolepsy. But now, some students, professionals and academics use it to boost their energy and brainpower.

Although Adrafinil is cheaper than Modafinil, doctors started prescribing Modafinil instead, as Adrafinil metabolised in the liver and could lead to serious side effects.

Adrafinil works by breaking down and forming Modafinil in the body. The recommended dosage of Adrafinil is 300mg to get the same effects as 100mg of Modafinil.

Watch: Nootropic Speed (Adrafinil) | What Do We Know About Adrafinil?

2. Caffeine

Caffeine, a natural stimulant, is often used as an alternative to prescription medications like Modafinil. You can find it in various foods and beverages, including coffee, tea, chocolate, and energy drinks.

Caffeine stimulates the central nervous system, increases alertness and concentration, and reduces fatigue. It does this by blocking the action of a neurotransmitter called adenosine, which helps regulate sleep and wakefulness.

Caffeine is considered safe when consumed in moderation and is widely used as a natural alternative to Modafinil. However, it can have adverse side effects if consumed in large amounts, including jitters, insomnia, and increased heart rate. 

It is essential to be mindful of your caffeine intake and to consume it in moderation to avoid adverse side effects.

3. L-Theanine

Centuries-old traditional medicine has utilised L-theanine, an amino acid found in tea leaves, as a natural substitute for prescription medications such as Modafinil.

L-theanine has several cognitive-enhancing effects, including improving focus and relaxation, reducing stress and anxiety, and increasing mental clarity. It is also calming and may help promote sleep.

Additionally, L-theanine increases the production of neurotransmitters in the brain, including serotonin and dopamine, which are responsible for mood and cognition. It also increases the production of alpha waves in the brain, which is associated with relaxation and mental clarity.

Importantly, theanine makes you more resistant to the adverse effects of caffeine. For this reason, a caffeine-theanine mix is a simple and popular nootropic that improves your wakefulness and cognitive performance without the downsides of a triple espresso.

4. Ginkgo Biloba

Many people prefer using Ginkgo biloba as a natural supplement instead of relying on prescription medications like Modafinil. This supplement comes from the leaves of the Ginkgo biloba tree, which originates from China and has a history of use in traditional medicine spanning centuries.

Ginkgo biloba enhances cognition in various ways, such as enhancing memory and concentration, alleviating stress and anxiety, and enhancing blood flow to the brain. Additionally, it frequently serves as a treatment for symptoms associated with Alzheimer’s disease and other forms of age-related cognitive decline.

One of Ginkgo biloba’s crucial active ingredients is an antioxidant that guards the brain against oxidative stress. Additionally, it is believed to house components that enhance blood flow to the brain and shield neurons from harm.

Scientific evidence endorses the use of Ginkgo biloba as a natural substitute for Modafinil. For instance, a review of 12 studies demonstrated that Ginkgo biloba may actively enhance cognitive function in individuals experiencing dementia and other forms of age-related cognitive decline. Another study confirmed that Ginkgo biloba noticeably improved memory and cognitive function in healthy young adults.

5. Brainzyme® FOCUS PRO™

Brainzyme® FOCUS PRO™ has been scientifically proven to support concentration, cognition, energy, memory and mental performance. It works fast, within an hour, and only uses 100% plant-powered ingredients that are legal in the UK.

modafinil alternatives

It is also great value for money, starting at 40p per capsule – much cheaper and more effective than a daily cup of coffee, other supplements or pharmaceutical study drugs, including Modafinil.

Brainzyme® FOCUS PRO™ vs Modafinil

See the table below for a direct comparison of Modafinil and Brainzyme® FOCUS PRO™.

ModafinilBrainzyme® FOCUS PRO™
Effectso Helps concentration, motivation, and wakefulness.
o Works fast (within an hour).
o Helps concentration, motivation, energy, and memory.
o Works fast (within an hour).
Side Effectso Headache & dry mouth.
o Sweating.
o Tapping/ restlessness.
o Feeling antisocial – may be impatient/ irritable.
o Anxiety if not doing what you want to do.
o Some reports of feeling thirsty.
Wakefulnesso Keeps you awake for a long time. Potentially longer than you want to.o Difficulty switching off.o Helps maintain wakefulness and alertness for up to 8 hours.
Focuso Helps give you the motivation and will to work and aids in reducing distractions.
o Assists in maintaining a natural and strong sense of focus.
Stimulationo Highly stimulating, causing agitation in some individuals.o Calms and focuses the mind with feeling motivated.
Toleranceo May cause tolerance, needing increased doses to have the same effect.o No issues with tolerance.
o Only available by prescription.
o May be screened for in sporting drug tests.
o Only available by prescription.
o May be screened for in sporting drugs tests.
o Readily available to buy & legal for sporting use.

Keep reading to discover why Brainzyme® FOCUS PRO™ is the best Modafinil alternative, or take advantage and save time by using the quick buy function.

 6. Panax Ginseng

Many people prefer using Panax ginseng as a natural supplement instead of relying on prescription medications like Modafinil. This supplement comes from the root of the Panax ginseng plant, which originates from Asia and has a history of use in traditional medicine spanning centuries.

Many believe that this herb has several cognitive-enhancing effects, such as improving memory and concentration, relieving stress and anxiety, and sharpening mental clarity.

Many believe it offers numerous other health benefits, including enhancing physical performance, reducing fatigue, and maintaining glucose levels. Additionally, it contains compounds that may aid in improving blood flow to the brain and safeguarding neurons from damage. Furthermore, it is believed that Panax ginseng regulates glucose levels, potentially supporting cognitive performance.

7. Acetyl L-Carnitine

Acetyl L-carnitine, also known as ALCAR, represents a modified version of the amino acid L-carnitine. The body naturally produces it, and it plays a role in energy metabolism, specifically in transporting fatty acids into the mitochondria for energy production. Certain foods like asparagus, dairy products, and poultry also contain small amounts of ALCAR.

Researchers have examined ALCAR for its potential to enhance brain function and alleviate age-related cognitive decline. It is believed to bolster the health of brain cells by shielding them from oxidative stress and encouraging the production of acetylcholine, a neurotransmitter crucial for learning and memory. ALCAR may also heighten blood flow to the brain and ramp up the generation of energy-producing mitochondria.

In addition to its cognitive benefits, ALCAR has undergone scrutiny for its potential to enhance physical performance, decrease fatigue, and promote healthy ageing. It may also possess antioxidant properties and have the capacity to safeguard against specific types of cell damage.

8. Choline

Choline is a nutrient imperative for the proper operation of the brain and nervous system. It serves as a precursor to the neurotransmitter acetylcholine, which plays a role in learning, memory, and muscle control. Choline also plays a role in generating phosphatidylcholine, a constituent of cell membranes, and in synthesising the neurotransmitter serotonin.

Studies have established that choline is crucial for brain development and function. It may bolster healthy cognitive function, including memory and learning, and provide protection against age-related cognitive decline. Additionally, choline may influence mood regulation and act as a preventative measure against anxiety and depression.

Choline is present in various foods, including eggs, liver, nuts, and legumes. It can also be taken in supplement form, either on its own or as part of a multivitamin.

9. Bacopa Monnieri

Bacopa monnieri, a perennial herb native to the wetlands of India, Australia, Europe, Africa, Asia, and North and South America, has a longstanding history in traditional Ayurvedic medicine. It is utilised as a brain tonic to enhance memory, learning, and cognitive function.

Bacopa monnieri contains compounds believed to bolster the health of the brain and nervous system by mending damaged neurons and facilitating the growth of new ones. It is also thought to heighten the activity of the neurotransmitter acetylcholine, which plays a pivotal role in learning and memory.

Research has shown that Bacopa monnieri may improve memory recall and processing speed in healthy adults and reduce symptoms of anxiety and depression. The herb may also improve attention and mental clarity in healthy individuals and those with cognitive decline.

It is available in supplement form and can be taken in capsule, tablet, or tincture form. It is generally considered safe when taken in recommended doses, but it can cause digestive issues in some people. As with any supplement, speaking with a healthcare provider before starting use is essential.

What is the Best Modafinil Alternative?

When determining the best Modafinil alternatives, it is essential to consider how these natural supplements will interact with each other. Many take more than one to take advantage of each supplement’s benefits.

However, taking many different supplements can be time-consuming, so a supplement stack is often better.

A supplement stack is a combination of dietary supplements that are taken together to achieve a specific health goal. Supplement stacks can be customised to meet individual needs and may include a variety of nutrients and herbs that support particular functions or systems in the body.

Of all the Modafinil alternatives on this list, only Brainzyme® FOCUS PRO™ is a supplement stack. In fact, some of its key ingredients, such as ginkgo biloba, choline, and L-theanine, are already on this list.

Brainzyme® FOCUS PRO™ comes in easy-to-swallow capsules that you can add to any morning routine. Taking two capsules once a day will give your brain the boost you need to stay focused all day long.

Modafinil’s main mechanism of action (by a large degree) is to act on the brain neurotransmitter ‘dopamine’. So if you want a powerful and natural alternative that works on the same neural pathway (and therefore has similar results), we recommend trying Brainzyme® FOCUS PRO™, our choice for the best Modafinil alternative.

Did You Know?

If you want to try an 

  • Affordable (at only £29) 
  • Legal 
  • Just as effective

Natural alternative today, you can get 10% off your very first purchase of Brainzyme® FOCUS PRO™! Use the code BRAINWAVE10 when checking out.


In conclusion, Modafinil is a prescription medication that improves wakefulness and cognitive function and commonly used off-label as a ‘smart pill’. While effective, it can also cause various side effects and may not be suitable for everyone.

We’d advise against using Modafinil as a study drug, as it is illegal in the UK and can cause unpleasant side effects. This is why we’d recommend natural alternatives that also work on the dopamine pathway, giving you a strong focus and concentration boost.

As you’ve just read, there are plenty of great natural alternatives to Modafinil. They are typically better value for money, equally or more effective, legal to use over the counter, and proven to have fewer side effects than Modafinil.

However, the best choice of Modafinil alternatives is a supplement stack that combines several of these supplements into one convenient option.

While several other natural options are available for boosting productivity and focus, as a 100% plant-powered, non-pharmaceutical, UK-made nootropic, the supplement stack, Brainzyme® FOCUS PRO™, was specifically designed to help improve your focus, energy, motivation, and memory. Thus, it stands out as the most comprehensive and effective natural Modafinil alternative.

That is why we strongly suggest buying Brainzyme® FOCUS PRO™ as a legal, affordable, and convenient alternative to Modafinil as a smart pill.


Silva-Brenes, D.V. et al. (2022) Out-smarting smart drug modafinil through Flow Chemistry, Green Chemistry. The Royal Society of Chemistry. Available at: (Accessed: November 11, 2022).

Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A comprehensive review, Battleday RM, Brem AK. doi:10.1016/j.euroneuro.2015.07.028. Eur Neuropsychopharmacol. 2015;25(11):1865-1881

Pro, M. (n.d.). Nootropics Benefits | Research-Based Results from the Smartest Brain-Boosters Benefits of Nootropics was retrieved from

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